One of R&B’s best-selling singing female trios in history has reunited—this time, to lift up Jesus.

Beyoncé Knowles and Kelly Rowland have hopped on Michelle Williams’ new up tempo inspirational track “Say Yes!” ahead of the release of the Destiny Child member’s gospel CD Journey To Freedom.

The pulsating beat with a reggae feel offers a new twist on a Nigerian hymn that says, “When Jesus say yes nobody can say no.”

Some are predicting that this tune, with the help of Williams’ R&B diva friends will be just the thing to push it to the #1 spot.

Your thoughts?